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Stimulatory Effect of Tofacitinib on Bone Marrow Adipocytes Differentiation

BACKGROUND: Systemic inflammation is the main factor underlying secondary osteoporosis in patients with rheumatoid arthritis (RA). Janus kinase inhibitors (JAKi), such as tofacitinib (Tofa), can control systemic inflammation and may have beneficial effects on bone in various models. This might be du...

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Detalles Bibliográficos
Autores principales: Letarouilly, Jean-Guillaume, Paccou, Julien, Badr, Sammy, Chauveau, Christophe, Broux, Odile, Clabaut, Aline
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9299421/
https://www.ncbi.nlm.nih.gov/pubmed/35873000
http://dx.doi.org/10.3389/fendo.2022.881699