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4‐Iodopyrimidine Labeling Reveals Nuclear Translocation and Nuclease Activity for Both MIF and MIF2

Macrophage migration inhibitory factor (MIF) and its homolog MIF2 (also known as D‐dopachrome tautomerase or DDT) play key roles in cell growth and immune responses. MIF and MIF2 expression is dysregulated in cancers and neurodegenerative diseases. Accurate and convenient detection of MIF and MIF2 w...

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Detalles Bibliográficos
Autores principales: Xiao, Zhangping, Chen, Deng, Mulder, Fabian, Song, Shanshan, van der Wouden, Petra E., Cool, Robbert H., Melgert, Barbro N., Poelarends, Gerrit J., Dekker, Frank J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9299485/
https://www.ncbi.nlm.nih.gov/pubmed/34724273
http://dx.doi.org/10.1002/chem.202103030