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Utility of a next‐generation framework for assessment of genomic damage: A case study using the pharmaceutical drug candidate etoposide

We present a hypothetical case study to examine the use of a next‐generation framework developed by the Genetic Toxicology Technical Committee of the Health and Environmental Sciences Institute for assessing the potential risk of genetic damage from a pharmaceutical perspective. We used etoposide, a...

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Detalles Bibliográficos
Autores principales: Nicolette, John, Luijten, Mirjam, Sasaki, Jennifer C., Custer, Laura, Embry, Michelle, Froetschl, Roland, Johnson, George, Ouedraogo, Gladys, Settivari, Raja, Thybaud, Veronique, Dearfield, Kerry L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9299499/
https://www.ncbi.nlm.nih.gov/pubmed/34775645
http://dx.doi.org/10.1002/em.22467