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Measles and Nipah virus assembly: Specific lipid binding drives matrix polymerization

Measles virus, Nipah virus, and multiple other paramyxoviruses cause disease outbreaks in humans and animals worldwide. The paramyxovirus matrix (M) protein mediates virion assembly and budding from host cell membranes. M is thus a key target for antivirals, but few high-resolution structures of par...

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Detalles Bibliográficos
Autores principales: Norris, Michael J., Husby, Monica L., Kiosses, William B., Yin, Jieyun, Saxena, Roopashi, Rennick, Linda J., Heiner, Anja, Harkins, Stephanie S., Pokhrel, Rudramani, Schendel, Sharon L., Hastie, Kathryn M., Landeras-Bueno, Sara, Salie, Zhe Li, Lee, Benhur, Chapagain, Prem P., Maisner, Andrea, Duprex, W. Paul, Stahelin, Robert V., Saphire, Erica Ollmann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9299542/
https://www.ncbi.nlm.nih.gov/pubmed/35857835
http://dx.doi.org/10.1126/sciadv.abn1440