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Microtubule-binding core of the tau protein

The protein tau associates with microtubules to maintain neuronal health. Posttranslational modifications of tau interfere with this binding, leading to tau aggregation in neurodegenerative disorders. Here, we use solid-state nuclear magnetic resonance (NMR) to investigate the structure of the micro...

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Detalles Bibliográficos
Autores principales: El Mammeri, Nadia, Dregni, Aurelio J., Duan, Pu, Wang, Harrison K., Hong, Mei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9299549/
https://www.ncbi.nlm.nih.gov/pubmed/35857846
http://dx.doi.org/10.1126/sciadv.abo4459