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Polymeric nanoparticles for dual-targeted theranostic gene delivery to hepatocellular carcinoma

Hepatocellular carcinoma (HCC) develops predominantly in the inflammatory environment of a cirrhotic liver caused by hepatitis, toxin exposure, or chronic liver disease. A targeted therapeutic approach is required to enable cancer killing without causing toxicity and liver failure. Poly(beta-amino-e...

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Detalles Bibliográficos
Autores principales: Vaughan, Hannah J., Zamboni, Camila G., Hassan, Laboni F., Radant, Nicholas P., Jacob, Desmond, Mease, Ronnie C., Minn, Il, Tzeng, Stephany Y., Gabrielson, Kathleen L., Bhardwaj, Pranshu, Guo, Xin, Francisco, David, Pomper, Martin G., Green, Jordan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9299552/
https://www.ncbi.nlm.nih.gov/pubmed/35857843
http://dx.doi.org/10.1126/sciadv.abo6406