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Cancer‐associated fibroblast‐derived exosomal microRNA‐20a suppresses the PTEN/PI3K‐AKT pathway to promote the progression and chemoresistance of non‐small cell lung cancer

BACKGROUND: Cancer‐associated fibroblasts (CAFs) contributes to overall tumor progression. In the current survey, we explored the ability of microRNA‐20a (miR‐20a) within these CAF‐derived exosomes to influence non‐small‐cell lung cancer (NSCLC) progression. MATERIALS AND METHODS: Normal tissue‐asso...

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Detalles Bibliográficos
Autores principales: Shi, Lin, Zhu, Weiliang, Huang, Yuanyuan, Zhuo, Lin, Wang, Siyun, Chen, Shaobing, Zhang, Bei, Ke, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9299573/
https://www.ncbi.nlm.nih.gov/pubmed/35857905
http://dx.doi.org/10.1002/ctm2.989