A Multi‐enzyme Cascade for the Biosynthesis of AICA Ribonucleoside Di‐ and Triphosphate

AICA (5′‐aminoimidazole‐4‐carboxamide) ribonucleotides with different phosphorylation levels are the pharmaceutically active metabolites of AICA nucleoside‐based drugs. The chemical synthesis of AICA ribonucleotides with defined phosphorylation is challenging and expensive. In this study, we describ...

Descripción completa

Detalles Bibliográficos
Autores principales: Eltoukhy, Lobna, Loderer, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9299608/
https://www.ncbi.nlm.nih.gov/pubmed/34859954
http://dx.doi.org/10.1002/cbic.202100596

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9299608/
https://www.ncbi.nlm.nih.gov/pubmed/34859954
http://dx.doi.org/10.1002/cbic.202100596

Ejemplares similares