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Negishi Cross‐Coupling Provides Alkylated Tryptophans and Tryptophan Regioisomers
Mild transition‐metal catalysed cross‐couplings enable direct functionalisation of biocatalytically halogenated tryptophans with alkyl iodides, representing a new alternative for late‐stage derivatisations of halogenated aromatic amino acids. Moreover, this strategy enables preparation of (homo)tryp...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9299634/ https://www.ncbi.nlm.nih.gov/pubmed/34713938 http://dx.doi.org/10.1002/chem.202103353 |