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Negishi Cross‐Coupling Provides Alkylated Tryptophans and Tryptophan Regioisomers

Mild transition‐metal catalysed cross‐couplings enable direct functionalisation of biocatalytically halogenated tryptophans with alkyl iodides, representing a new alternative for late‐stage derivatisations of halogenated aromatic amino acids. Moreover, this strategy enables preparation of (homo)tryp...

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Detalles Bibliográficos
Autores principales: Dachwitz, Steffen, Scharkowski, Bjarne, Sewald, Norbert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9299634/
https://www.ncbi.nlm.nih.gov/pubmed/34713938
http://dx.doi.org/10.1002/chem.202103353