Sortase‐Mediated Multi‐Fragment Assemblies by Ligation Site Switching

Sortase‐mediated ligation (SML) is a powerful tool of protein chemistry allowing the ligation of peptides containing LPxTG sorting motifs and N‐terminal glycine nucleophiles. The installation of a sorting motif into the product prohibits the assembly of multiple fragments by SML. Here we report mult...

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Detalles Bibliográficos
Autores principales: Bierlmeier, Jan, Álvaro‐Benito, Miguel, Scheffler, Maren, Sturm, Kristina, Rehkopf, Luisa, Freund, Christian, Schwarzer, Dirk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9299656/
https://www.ncbi.nlm.nih.gov/pubmed/34735044
http://dx.doi.org/10.1002/anie.202109032

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9299656/
https://www.ncbi.nlm.nih.gov/pubmed/34735044
http://dx.doi.org/10.1002/anie.202109032

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