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Dupilumab in CRSwNP: Responder Analysis Using Clinically Meaningful Efficacy Outcome Thresholds

OBJECTIVES/HYPOTHESIS: Dupilumab, a fully human monoclonal antibody that blocks the shared interleukin (IL)‐4/IL‐13 receptor component, significantly improved outcomes for patients with chronic rhinosinusitis with nasal polyps (CRSwNP) in the SINUS‐24 and SINUS‐52 studies. This post hoc analysis eva...

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Detalles Bibliográficos
Autores principales: Chuang, Chien‐Chia, Guillemin, Isabelle, Bachert, Claus, Lee, Stella E., Hellings, Peter W., Fokkens, Wytske J., Duverger, Nicolas, Fan, Chunpeng, Daizadeh, Nadia, Amin, Nikhil, Mannent, Leda P., Khan, Asif H., Kamat, Siddhesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9299704/
https://www.ncbi.nlm.nih.gov/pubmed/34817082
http://dx.doi.org/10.1002/lary.29911