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Dysregulation of RalA signaling through dual regulatory mechanisms exerts its oncogenic functions in hepatocellular carcinoma

BACKGROUND AND AIMS: Ras‐like (Ral) small guanosine triphosphatases (GTPases), RalA and RalB, are proto‐oncogenes directly downstream of Ras and cycle between the active guanosine triphosphate‐bound and inactive guanosine diphosphate‐bound forms. RalGTPase‐activating protein (RalGAP) complex exerts...

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Detalles Bibliográficos
Autores principales: Tian, Lu, Zhao, Luqing, Sze, Karen Man‐Fong, Kam, Charles Shing, Ming, Vanessa Sheung‐In, Wang, Xia, Zhang, Vanilla Xin, Ho, Daniel Wai‐Hung, Cheung, Tan‐To, Chan, Lo‐Kong, Ng, Irene Oi‐Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9299834/
https://www.ncbi.nlm.nih.gov/pubmed/34767674
http://dx.doi.org/10.1002/hep.32236