A Conformationally Stable Acyclic β‐Hairpin Scaffold Tolerating the Incorporation of Poorly β‐Sheet‐Prone Amino Acids

The β‐hairpin is a structural element of native proteins, but it is also a useful artificial scaffold for finding lead compounds to convert into peptidomimetics or non‐peptide structures for drug discovery. Since linear peptides are synthetically more easily accessible than cyclic ones, but are stru...

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Detalles Bibliográficos
Autores principales: Stanojlovic, Vesna, Müller, Anna, Moazzam, Ali, Hinterholzer, Arthur, Ożga, Katarzyna, Berlicki, Łukasz, Schubert, Mario, Cabrele, Chiara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9299858/
https://www.ncbi.nlm.nih.gov/pubmed/34856053
http://dx.doi.org/10.1002/cbic.202100604

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9299858/
https://www.ncbi.nlm.nih.gov/pubmed/34856053
http://dx.doi.org/10.1002/cbic.202100604

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