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Total Synthesis of Pulvomycin D

A synthetic route to the pulvomycin class of natural products is presented, which culminated in the first synthesis of a pulvomycin, pulvomycin D. Key elements of the strategy include a pivotal aldol reaction which led to bond formation between the C24‐C40 and the C8‐C23 fragment. The remaining C1‐C...

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Detalles Bibliográficos
Autores principales: Fritz, Lukas, Wienhold, Sebastian, Hackl, Sabrina, Bach, Thorsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9299864/
https://www.ncbi.nlm.nih.gov/pubmed/34792826
http://dx.doi.org/10.1002/chem.202104064