Hepatitis E virus infection activates NOD‐like receptor family pyrin domain‐containing 3 inflammasome antagonizing interferon response but therapeutically targetable

BACKGROUND AND AIMS: HEV infection is the most common cause of liver inflammation, but the pathogenic mechanisms remain largely unclear. We aim to explore whether HEV infection activates inflammasomes, crosstalk with antiviral interferon response, and the potential of therapeutic targeting. APPROACH...

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Detalles Bibliográficos
Autores principales: Li, Yang, Yu, Peifa, Kessler, Amy L., Shu, Jingyi, Liu, Xiaoyan, Liang, Zhaochao, Liu, Jiaye, Li, Yunlong, Li, Pengfei, Wang, Ling, Wang, Yining, Ma, Zhongren, Liu, Aixia, Bruno, Marco J., de Man, Robert A., Peppelenbosch, Maikel P., Buschow, Sonja I., Wang, Lin, Wang, Yijin, Pan, Qiuwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9299901/
https://www.ncbi.nlm.nih.gov/pubmed/34392558
http://dx.doi.org/10.1002/hep.32114

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9299901/
https://www.ncbi.nlm.nih.gov/pubmed/34392558
http://dx.doi.org/10.1002/hep.32114

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