Cargando…

A Modular Approach to the Antifungal Sphingofungin Family: Concise Total Synthesis of Sphingofungin A and C

Sphingofungins are fungal natural products known to inhibit the biosynthesis of sphingolipids which play pivotal roles in various cell functions. Here, we report a short and flexible synthetic approach towards the sphingofungin family. Key step of the synthesis was a decarboxylative cross‐coupling r...

Descripción completa

Detalles Bibliográficos
Autores principales: Raguž, Luka, Peng, Chia‐Chi, Kaiser, Marcel, Görls, Helmar, Beemelmanns, Christine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9300042/
https://www.ncbi.nlm.nih.gov/pubmed/34677894
http://dx.doi.org/10.1002/anie.202112616