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Characterization of Structure and Dynamics of the Guanidine‐II Riboswitch from Escherichia coli by NMR Spectroscopy and Small‐Angle X‐ray Scattering (SAXS)

Riboswitches are regulatory RNA elements that undergo functionally important allosteric conformational switching upon binding of specific ligands. The here investigated guanidine‐II riboswitch binds the small cation, guanidinium, and forms a kissing loop‐loop interaction between its P1 and P2 hairpi...

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Detalles Bibliográficos
Autores principales: Schamber, Tatjana, Binas, Oliver, Schlundt, Andreas, Wacker, Anna, Schwalbe, Harald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9300104/
https://www.ncbi.nlm.nih.gov/pubmed/34847270
http://dx.doi.org/10.1002/cbic.202100564