Biogenesis of hepatitis B virus e antigen is driven by translocon‐associated protein complex and regulated by conserved cysteine residues within its signal peptide sequence

Hepatitis B virus uses e antigen (HBe), which is dispensable for virus infectivity, to modulate host immune responses and achieve viral persistence in human hepatocytes. The HBe precursor (p25) is directed to the endoplasmic reticulum (ER), where cleavage of the signal peptide (sp) gives rise to the...

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Detalles Bibliográficos
Autores principales: Zábranská, Helena, Zábranský, Aleš, Lubyová, Barbora, Hodek, Jan, Křenková, Alena, Hubálek, Martin, Weber, Jan, Pichová, Iva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9300162/
https://www.ncbi.nlm.nih.gov/pubmed/34839586
http://dx.doi.org/10.1111/febs.16304

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9300162/
https://www.ncbi.nlm.nih.gov/pubmed/34839586
http://dx.doi.org/10.1111/febs.16304

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