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Peroxisome proliferator‐activated receptor gamma coactivator 1‐alpha protects a fibrotic liver from partial hepatectomy‐induced advanced liver injury through regulating cell cycle arrest

BACKGROUND: A fibrotic liver may have an impaired regenerative capacity. Because liver transplantation is donor limited, understanding the regenerative ability of a fibrotic liver is important. METHODS: A two‐thirds partial hepatectomy (PH) was performed in C57Bl/6 mice with or without carbon tetrac...

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Detalles Bibliográficos
Autores principales: Zhang, Linzhong, Wang, Wei, Liu, Lipeng, Zhang, Yanghao, Zhang, Xiuying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9300180/
https://www.ncbi.nlm.nih.gov/pubmed/34845850
http://dx.doi.org/10.1111/bcpt.13697