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Astragaloside IV Protects Detrusor from Partial Bladder Outlet Obstruction-Induced Oxidative Stress by Activating Mitophagy through AMPK-ULK1 Pathway

AIMS: Bladder outlet obstruction (BOO) and the consequent low contractility of detrusor are the leading causes of voiding dysfunction. In this study, we aimed to evaluate the pharmacological activity of astragaloside IV (AS-IV), an antioxidant biomolecule that possess beneficial effect in many organ...

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Detalles Bibliográficos
Autores principales: Zhu, Xiaoyu, Tao, Fangze, Zhang, Li, Yu, Yajie, Xu, Yanchao, Yang, Gang, Wei, Zhifeng, Cheng, Yidong, Yin, Xuelai, Zhang, Xinyuan, Wei, Wu, Wang, Anxi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9300277/
https://www.ncbi.nlm.nih.gov/pubmed/35873803
http://dx.doi.org/10.1155/2022/5757367