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Inhibition of SphK1/S1P Signaling Pathway Alleviates Fibrosis and Inflammation of Rat Myocardium after Myocardial Infarction

OBJECTIVE: The sphingosine kinase 1 (SphK1)/sphingosine-1-phosphate (S1P) signaling pathway is involved in fibrosis and inflammatory responses of myocardial tissue after myocardial infarction (MI). The purpose of our study was to explore the role of SphK1/S1P signaling pathway in myocardial injury a...

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Detalles Bibliográficos
Autores principales: Wu, Xiaokui, Xu, Junwei, Li, Xiangyu, Dai, Jian, Wang, Linlin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9300330/
https://www.ncbi.nlm.nih.gov/pubmed/35872958
http://dx.doi.org/10.1155/2022/5985375