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Nuclear chromosome locations dictate segregation error frequencies
Chromosome segregation errors during cell divisions generate aneuploidies and micronuclei, which can undergo extensive chromosomal rearrangements such as chromothripsis(1–5). Selective pressures then shape distinct aneuploidy and rearrangement patterns—for example, in cancer(6,7)—but it is unknown w...
Autores principales: | , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9300461/ https://www.ncbi.nlm.nih.gov/pubmed/35831506 http://dx.doi.org/10.1038/s41586-022-04938-0 |