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Nuclear chromosome locations dictate segregation error frequencies

Chromosome segregation errors during cell divisions generate aneuploidies and micronuclei, which can undergo extensive chromosomal rearrangements such as chromothripsis(1–5). Selective pressures then shape distinct aneuploidy and rearrangement patterns—for example, in cancer(6,7)—but it is unknown w...

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Detalles Bibliográficos
Autores principales: Klaasen, Sjoerd J., Truong, My Anh, van Jaarsveld, Richard H., Koprivec, Isabella, Štimac, Valentina, de Vries, Sippe G., Risteski, Patrik, Kodba, Snježana, Vukušić, Kruno, de Luca, Kim L., Marques, Joana F., Gerrits, Elianne M., Bakker, Bjorn, Foijer, Floris, Kind, Jop, Tolić, Iva M., Lens, Susanne M. A., Kops, Geert J. P. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9300461/
https://www.ncbi.nlm.nih.gov/pubmed/35831506
http://dx.doi.org/10.1038/s41586-022-04938-0