Cargando…
Nuclear chromosome locations dictate segregation error frequencies
Chromosome segregation errors during cell divisions generate aneuploidies and micronuclei, which can undergo extensive chromosomal rearrangements such as chromothripsis(1–5). Selective pressures then shape distinct aneuploidy and rearrangement patterns—for example, in cancer(6,7)—but it is unknown w...
Autores principales: | Klaasen, Sjoerd J., Truong, My Anh, van Jaarsveld, Richard H., Koprivec, Isabella, Štimac, Valentina, de Vries, Sippe G., Risteski, Patrik, Kodba, Snježana, Vukušić, Kruno, de Luca, Kim L., Marques, Joana F., Gerrits, Elianne M., Bakker, Bjorn, Foijer, Floris, Kind, Jop, Tolić, Iva M., Lens, Susanne M. A., Kops, Geert J. P. L. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9300461/ https://www.ncbi.nlm.nih.gov/pubmed/35831506 http://dx.doi.org/10.1038/s41586-022-04938-0 |
Ejemplares similares
-
Microtubule-sliding modules based on kinesins EG5 and PRC1-dependent KIF4A drive human spindle elongation
por: Vukušić, Kruno, et al.
Publicado: (2021) -
Anaphase B: Long-standing models meet new concepts
por: Vukušić, Kruno, et al.
Publicado: (2021) -
Polar Chromosomes—Challenges of a Risky Path
por: Vukušić, Kruno, et al.
Publicado: (2022) -
Microtubule Sliding within the Bridging Fiber Pushes Kinetochore Fibers Apart to Segregate Chromosomes
por: Vukušić, Kruno, et al.
Publicado: (2017) -
Augmin prevents merotelic attachments by promoting proper arrangement of bridging and kinetochore fibers
por: Štimac, Valentina, et al.
Publicado: (2022)