Mitochondrial RNA modifications shape metabolic plasticity in metastasis

Aggressive and metastatic cancers show enhanced metabolic plasticity(1), but the precise underlying mechanisms of this remain unclear. Here we show how two NOP2/Sun RNA methyltransferase 3 (NSUN3)-dependent RNA modifications—5-methylcytosine (m(5)C) and its derivative 5-formylcytosine (f(5)C) (refs....

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Detalles Bibliográficos
Autores principales: Delaunay, Sylvain, Pascual, Gloria, Feng, Bohai, Klann, Kevin, Behm, Mikaela, Hotz-Wagenblatt, Agnes, Richter, Karsten, Zaoui, Karim, Herpel, Esther, Münch, Christian, Dietmann, Sabine, Hess, Jochen, Benitah, Salvador Aznar, Frye, Michaela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9300468/
https://www.ncbi.nlm.nih.gov/pubmed/35768510
http://dx.doi.org/10.1038/s41586-022-04898-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9300468/
https://www.ncbi.nlm.nih.gov/pubmed/35768510
http://dx.doi.org/10.1038/s41586-022-04898-5

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