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The E3 ubiquitin ligase MG53 inhibits hepatocellular carcinoma by targeting RAC1 signaling

Ras-related C3 botulinum toxin substrate 1 (RAC1) overexpressiosn and hyperactivation are correlated with aggressive growth and other malignant characteristics in a wide variety of cancers including hepatocellular carcinoma (HCC). However, the regulatory mechanism of RAC1 expression and activation i...

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Detalles Bibliográficos
Autores principales: Ma, Xiaomin, Ma, Xiaoxiao, Zhu, Lihui, Zhao, Yunxue, Chen, Mengmeng, Li, Tao, Lin, Yueke, Ma, Dapeng, Sun, Caiyu, Han, Lihui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9300626/
https://www.ncbi.nlm.nih.gov/pubmed/35858925
http://dx.doi.org/10.1038/s41389-022-00414-6