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Model-guided engineering of DNA sequences with predictable site-specific recombination rates
Site-specific recombination (SSR) is an important tool in synthetic biology, but its applications are limited by the inability to predictably tune SSR reaction rates. Facile rate manipulation could be achieved by modifying the DNA substrate sequence; however, this approach lacks rational design prin...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9300676/ https://www.ncbi.nlm.nih.gov/pubmed/35858965 http://dx.doi.org/10.1038/s41467-022-31538-3 |