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Polycomb-lamina antagonism partitions heterochromatin at the nuclear periphery

The genome can be divided into two spatially segregated compartments, A and B, which partition active and inactive chromatin states. While constitutive heterochromatin is predominantly located within the B compartment near the nuclear lamina, facultative heterochromatin marked by H3K27me3 spans both...

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Detalles Bibliográficos
Autores principales: Siegenfeld, Allison P., Roseman, Shelby A., Roh, Heejin, Lue, Nicholas Z., Wagen, Corin C., Zhou, Eric, Johnstone, Sarah E., Aryee, Martin J., Liau, Brian B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9300685/
https://www.ncbi.nlm.nih.gov/pubmed/35859152
http://dx.doi.org/10.1038/s41467-022-31857-5