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Neuropilin 1 and its inhibitory ligand mini-tryptophanyl-tRNA synthetase inversely regulate VE-cadherin turnover and vascular permeability

The formation of a functional blood vessel network relies on the ability of endothelial cells (ECs) to dynamically rearrange their adhesive contacts in response to blood flow and guidance cues, such as vascular endothelial growth factor-A (VEGF-A) and class 3 semaphorins (SEMA3s). Neuropilin 1 (NRP1...

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Detalles Bibliográficos
Autores principales: Gioelli, Noemi, Neilson, Lisa J., Wei, Na, Villari, Giulia, Chen, Wenqian, Kuhle, Bernhard, Ehling, Manuel, Maione, Federica, Willox, Sander, Brundu, Serena, Avanzato, Daniele, Koulouras, Grigorios, Mazzone, Massimiliano, Giraudo, Enrico, Yang, Xiang-Lei, Valdembri, Donatella, Zanivan, Sara, Serini, Guido
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9300702/
https://www.ncbi.nlm.nih.gov/pubmed/35858913
http://dx.doi.org/10.1038/s41467-022-31904-1