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Neuropilin 1 and its inhibitory ligand mini-tryptophanyl-tRNA synthetase inversely regulate VE-cadherin turnover and vascular permeability
The formation of a functional blood vessel network relies on the ability of endothelial cells (ECs) to dynamically rearrange their adhesive contacts in response to blood flow and guidance cues, such as vascular endothelial growth factor-A (VEGF-A) and class 3 semaphorins (SEMA3s). Neuropilin 1 (NRP1...
Autores principales: | Gioelli, Noemi, Neilson, Lisa J., Wei, Na, Villari, Giulia, Chen, Wenqian, Kuhle, Bernhard, Ehling, Manuel, Maione, Federica, Willox, Sander, Brundu, Serena, Avanzato, Daniele, Koulouras, Grigorios, Mazzone, Massimiliano, Giraudo, Enrico, Yang, Xiang-Lei, Valdembri, Donatella, Zanivan, Sara, Serini, Guido |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9300702/ https://www.ncbi.nlm.nih.gov/pubmed/35858913 http://dx.doi.org/10.1038/s41467-022-31904-1 |
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