Cell-free DNA 5-hydroxymethylcytosine is an emerging marker of acute myeloid leukemia

Aberrant changes in 5-hydroxymethylcytosine (5hmC) are a unique epigenetic feature in many cancers including acute myeloid leukemia (AML). However, genome-wide analysis of 5hmC in plasma cell-free DNA (cfDNA) remains unexploited in AML patients. We used a highly sensitive and robust nano-5hmC-Seal t...

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Detalles Bibliográficos
Autores principales: Shao, Jianming, Wang, Sihan, West-Szymanski, Diana, Karpus, Jason, Shah, Shilpan, Ganguly, Siddhartha, Smith, Janice, Zu, Youli, He, Chuan, Li, Zejuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9300744/
https://www.ncbi.nlm.nih.gov/pubmed/35859008
http://dx.doi.org/10.1038/s41598-022-16685-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9300744/
https://www.ncbi.nlm.nih.gov/pubmed/35859008
http://dx.doi.org/10.1038/s41598-022-16685-3

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