Dynamics of Melanoma-Associated Epitope-Specific CD8+ T Cells in the Blood Correlate With Clinical Outcome Under PD-1 Blockade

Immune checkpoint blockade (ICB) is standard-of-care for patients with metastatic melanoma. It may re-invigorate T cells recognizing tumors, and several tumor antigens have been identified as potential targets. However, little is known about the dynamics of tumor antigen-specific T cells in the circ...

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Detalles Bibliográficos
Autores principales: Gaißler, Andrea, Meldgaard, Trine Sundebo, Heeke, Christina, Babaei, Sepideh, Tvingsholm, Siri Amanda, Bochem, Jonas, Spreuer, Janine, Amaral, Teresa, Wagner, Nikolaus Benjamin, Klein, Reinhild, Meier, Friedegund, Garbe, Claus, Eigentler, Thomas K., Pawelec, Graham, Claassen, Manfred, Weide, Benjamin, Hadrup, Sine Reker, Wistuba-Hamprecht, Kilian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9300827/
https://www.ncbi.nlm.nih.gov/pubmed/35874702
http://dx.doi.org/10.3389/fimmu.2022.906352

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9300827/
https://www.ncbi.nlm.nih.gov/pubmed/35874702
http://dx.doi.org/10.3389/fimmu.2022.906352

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