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Dynamics of Melanoma-Associated Epitope-Specific CD8+ T Cells in the Blood Correlate With Clinical Outcome Under PD-1 Blockade
Immune checkpoint blockade (ICB) is standard-of-care for patients with metastatic melanoma. It may re-invigorate T cells recognizing tumors, and several tumor antigens have been identified as potential targets. However, little is known about the dynamics of tumor antigen-specific T cells in the circ...
Autores principales: | Gaißler, Andrea, Meldgaard, Trine Sundebo, Heeke, Christina, Babaei, Sepideh, Tvingsholm, Siri Amanda, Bochem, Jonas, Spreuer, Janine, Amaral, Teresa, Wagner, Nikolaus Benjamin, Klein, Reinhild, Meier, Friedegund, Garbe, Claus, Eigentler, Thomas K., Pawelec, Graham, Claassen, Manfred, Weide, Benjamin, Hadrup, Sine Reker, Wistuba-Hamprecht, Kilian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9300827/ https://www.ncbi.nlm.nih.gov/pubmed/35874702 http://dx.doi.org/10.3389/fimmu.2022.906352 |
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