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External Evaluation of Population Pharmacokinetic Models of Busulfan in Chinese Adult Hematopoietic Stem Cell Transplantation Recipients

Objective: Busulfan (BU) is a bi-functional DNA-alkylating agent used in patients undergoing hematopoietic stem cell transplantation (HSCT). Over the last decades, several population pharmacokinetic (pop PK) models of BU have been established, but external evaluation has not been performed for almos...

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Detalles Bibliográficos
Autores principales: Huang, Huiping, Liu, Qingxia, Zhang, Xiaohan, Xie, Helin, Liu, Maobai, Chaphekar, Nupur, Wu, Xuemei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9300831/
https://www.ncbi.nlm.nih.gov/pubmed/35873594
http://dx.doi.org/10.3389/fphar.2022.835037