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The Emerging Roles of Rad51 in Cancer and Its Potential as a Therapeutic Target

Defects in DNA repair pathways are emerging hallmarks of cancer. Accurate DNA repairs and replications are essential for genomic stability. Cancer cells require residual DNA repair capabilities to repair the damage from replication stress and genotoxic anti-tumor agents. Defective DNA repair also pr...

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Detalles Bibliográficos
Autores principales: Wang, Ziyi, Jia, Renxiang, Wang, Linlin, Yang, Qiwei, Hu, Xiaohai, Fu, Qiang, Zhang, Xinyu, Li, Wenya, Ren, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9300834/
https://www.ncbi.nlm.nih.gov/pubmed/35875146
http://dx.doi.org/10.3389/fonc.2022.935593