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A Preliminary in vitro and in vivo Evaluation of the Effect and Action Mechanism of 17-AAG Combined With Azoles Against Azole-Resistant Candida spp.

Invasive candidiasis is the primary reason for the increased cases of mortality in a medical environment. The resistance spectra of Candida species to antifungal drugs have gradually expanded. Particularly, the resistance spectra of Candida auris are the most prominent. Hsp90 plays a protective role...

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Detalles Bibliográficos
Autores principales: Liu, Luyao, Zhang, Xueying, Kayastha, Shruti, Tan, Lihua, Zhang, Heng, Tan, Jingwen, Li, Linyun, Mao, Jinghua, Sun, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9300965/
https://www.ncbi.nlm.nih.gov/pubmed/35875545
http://dx.doi.org/10.3389/fmicb.2022.825745