Deletion of microRNA-183-96-182 Cluster in Lymphocytes Suppresses Anti-DsDNA Autoantibody Production and IgG Deposition in the Kidneys in C57BL/6-Fas(lpr/lpr) Mice

Dysregulated miRNAs have been implicated in the pathogenesis of systemic lupus erythematosus (SLE). Our previous study reported a substantial increase in three miRNAs located at the miR-183-96-182 cluster (miR-183C) in several autoimmune lupus-prone mice, including MRL/lpr and C57BL/6-lpr (B6/lpr)....

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Zhuang, Heid, Bettina, Lu, Ran, Sachdeva, Mohit, Edwards, Michael R., Ren, JingJing, Cecere, Thomas E., Khan, Deena, Jeboda, Taschua, Kirsch, David G., Reilly, Christopher M., Dai, Rujuan, Ahmed, S. Ansar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9301314/
https://www.ncbi.nlm.nih.gov/pubmed/35873462
http://dx.doi.org/10.3389/fgene.2022.840060

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9301314/
https://www.ncbi.nlm.nih.gov/pubmed/35873462
http://dx.doi.org/10.3389/fgene.2022.840060

Ejemplares similares