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IL-7 Promotes the Expansion of Circulating CD28- Cytotoxic T Lymphocytes in Patients With IgG4-Related Disease via the JAK Signaling

OBJECTIVES: This study aimed to elucidate the changes and associated mechanisms of circulating CD28- cytotoxic T lymphocytes (CTLs) in patients with IgG4-related disease (IgG4-RD). METHODS: Fifty IgG4-RD patients and 15 healthy controls (HCs) were recruited. Peripheral blood mononuclear cells (PBMCs...

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Detalles Bibliográficos
Autores principales: Xia, Chang-sheng, Long, Yan, Liu, Yanying, Alifu, Aikede, Zeng, Xingyue, Liu, Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9301466/
https://www.ncbi.nlm.nih.gov/pubmed/35874706
http://dx.doi.org/10.3389/fimmu.2022.922307