Structural New Data for Mitochondrial Peroxiredoxin From Trypanosoma cruzi Show High Similarity With Human Peroxiredoxin 3: Repositioning Thiostrepton as Antichagasic Drug

Trypanosoma cruzi, the causal agent of Chagas disease, has peroxiredoxins (PRXs) expressed in all stages of the parasite and whose function is to detoxify oxidizing agents, such as reactive oxygen species (ROS). These proteins are central for the survival and replication of the parasite and have bee...

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Detalles Bibliográficos
Autores principales: Rivera-Santiago, Lucio, Martínez, Ignacio, Arroyo-Olarte, Ruben, Díaz-Garrido, Paulina, Cuevas-Hernandez, Roberto I., Espinoza, Bertha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cellular and Infection Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9301493/
https://www.ncbi.nlm.nih.gov/pubmed/35873171
http://dx.doi.org/10.3389/fcimb.2022.907043

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9301493/
https://www.ncbi.nlm.nih.gov/pubmed/35873171
http://dx.doi.org/10.3389/fcimb.2022.907043

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