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Exploring the function of factor XIII free B subunit: Interactions with complement factors and a novel approach to identify potential binding partners

BACKGROUND: The factor XIII (FXIII)‐B subunit has a critical function as a carrier protein to stabilize FXIII‐A in plasma and supply it to its main substrate, fibrinogen. However, the function of the excess free FXIII‐B circulating in plasma is still elusive. OBJECTIVES: In the present study, we exp...

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Detalles Bibliográficos
Autores principales: Li, Bojun, Bechtler, Clément, Jenny, Lorenz, Ricklin, Daniel, Schroeder, Verena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9301527/
https://www.ncbi.nlm.nih.gov/pubmed/35873217
http://dx.doi.org/10.1002/rth2.12766