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The Q-junction and the inflammatory response are critical pathological and therapeutic factors in CoQ deficiency

Defects in Coenzyme Q (CoQ) metabolism have been associated with primary mitochondrial disorders, neurodegenerative diseases and metabolic conditions. The consequences of CoQ deficiency have not been fully addressed, and effective treatment remains challenging. Here, we use mice with primary CoQ def...

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Detalles Bibliográficos
Autores principales: González-García, Pilar, Díaz-Casado, María Elena, Hidalgo-Gutiérrez, Agustín, Jiménez-Sánchez, Laura, Bakkali, Mohammed, Barriocanal-Casado, Eliana, Escames, Germaine, Chiozzi, Riccardo Zenezini, Völlmy, Franziska, Zaal, Esther A., Berkers, Celia R., Heck, Albert J.R., López, Luis C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9301574/
https://www.ncbi.nlm.nih.gov/pubmed/35863266
http://dx.doi.org/10.1016/j.redox.2022.102403