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The Q-junction and the inflammatory response are critical pathological and therapeutic factors in CoQ deficiency
Defects in Coenzyme Q (CoQ) metabolism have been associated with primary mitochondrial disorders, neurodegenerative diseases and metabolic conditions. The consequences of CoQ deficiency have not been fully addressed, and effective treatment remains challenging. Here, we use mice with primary CoQ def...
Autores principales: | González-García, Pilar, Díaz-Casado, María Elena, Hidalgo-Gutiérrez, Agustín, Jiménez-Sánchez, Laura, Bakkali, Mohammed, Barriocanal-Casado, Eliana, Escames, Germaine, Chiozzi, Riccardo Zenezini, Völlmy, Franziska, Zaal, Esther A., Berkers, Celia R., Heck, Albert J.R., López, Luis C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9301574/ https://www.ncbi.nlm.nih.gov/pubmed/35863266 http://dx.doi.org/10.1016/j.redox.2022.102403 |
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