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Chronic Administration of COVID-19 Drugs Fluvoxamine and Lopinavir Shortens Action Potential Duration by Inhibiting the Human Ether‐à‐go‐go–Related Gene and Cav1.2

Background: Old drugs for new indications in the novel coronavirus disease of 2019 (COVID-19) pandemic have raised concerns regarding cardiotoxicity, especially the development of drug-induced QT prolongation. The acute blocking of the cardiac hERG potassium channel is conventionally thought to be t...

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Detalles Bibliográficos
Autores principales: Zheng, Zequn, Cai, Dihui, Fu, Yin, Wang, Ying, Song, Yongfei, Lian, Jiangfang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9301601/
https://www.ncbi.nlm.nih.gov/pubmed/35873575
http://dx.doi.org/10.3389/fphar.2022.889713