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Hypothermia Prevents Cardiac Dysfunction during Acute Ischemia Reperfusion by Maintaining Mitochondrial Bioenergetics and by Promoting Hexokinase II Binding to Mitochondria

BACKGROUND: Hypothermia (H), cardioplegia (CP), and both combined (HCP) are known to be protective against myocardial ischemia reperfusion (IR) injury. Mitochondria have molecular signaling mechanisms that are associated with both cell survival and cell death. In this study, we investigated the dyna...

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Detalles Bibliográficos
Autores principales: Sun, Jie, Mishra, Jyotsna, Yang, Meiying, Stowe, David F., Heisner, James S., An, Jianzhong, Kwok, Wai-Meng, Camara, Amadou K. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9301761/
https://www.ncbi.nlm.nih.gov/pubmed/35873800
http://dx.doi.org/10.1155/2022/4476448