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Hypothermia Prevents Cardiac Dysfunction during Acute Ischemia Reperfusion by Maintaining Mitochondrial Bioenergetics and by Promoting Hexokinase II Binding to Mitochondria
BACKGROUND: Hypothermia (H), cardioplegia (CP), and both combined (HCP) are known to be protective against myocardial ischemia reperfusion (IR) injury. Mitochondria have molecular signaling mechanisms that are associated with both cell survival and cell death. In this study, we investigated the dyna...
Autores principales: | Sun, Jie, Mishra, Jyotsna, Yang, Meiying, Stowe, David F., Heisner, James S., An, Jianzhong, Kwok, Wai-Meng, Camara, Amadou K. S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9301761/ https://www.ncbi.nlm.nih.gov/pubmed/35873800 http://dx.doi.org/10.1155/2022/4476448 |
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