Preinduced reovirus-specific T-cell immunity enhances the anticancer efficacy of reovirus therapy

BACKGROUND: Many solid tumors do not respond to immunotherapy due to their immunologically cold tumor microenvironment (TME). We and others found that oncolytic viruses (OVs), including reovirus type 3 Dearing, can enhance the efficacy of immunotherapy by recruiting CD8(+) T cells to the TME. A sign...

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Detalles Bibliográficos
Autores principales: Groeneveldt, Christianne, Kinderman, Priscilla, van Stigt Thans, Jordi J C, Labrie, Camilla, Griffioen, Lisa, Sluijter, Marjolein, van den Wollenberg, Diana J M, Hoeben, Rob C, den Haan, Joke M M, van der Burg, Sjoerd H, van Hall, Thorbald, van Montfoort, Nadine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Oncolytic and Local Immunotherapy
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9301813/
https://www.ncbi.nlm.nih.gov/pubmed/35853671
http://dx.doi.org/10.1136/jitc-2021-004464

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9301813/
https://www.ncbi.nlm.nih.gov/pubmed/35853671
http://dx.doi.org/10.1136/jitc-2021-004464

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