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Targeted demethylation of the SLC5A7 promotor inhibits colorectal cancer progression

BACKGROUND: SLC5A7 (solute carrier family 5 member 7), also known as choline transporter 1 (CHT1), is downregulated in colorectal cancer (CRC) and functions as a tumor suppressor. However, the mechanisms underlying the inactivation of SLC5A7 in CRC remain to be elucidated. RESULTS: In the present st...

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Detalles Bibliográficos
Autores principales: Li, Yang, Liu, Baike, Yin, Xiaonan, Jiang, Zhiyuan, Fang, Chao, Chen, Na, Zhang, Bo, Dai, Lei, Yin, Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9301853/
https://www.ncbi.nlm.nih.gov/pubmed/35858918
http://dx.doi.org/10.1186/s13148-022-01308-5