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Neuropilin-1 cooperates with PD-1 in CD8(+) T cells predicting outcomes in melanoma patients treated with anti-PD1

Targeting immune checkpoints, such as Programmed cell Death 1 (PD1), has improved survival in cancer patients by restoring antitumor immune responses. Most patients, however, relapse or are refractory to immune checkpoint blocking therapies. Neuropilin-1 (NRP1) is a transmembrane glycoprotein requir...

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Detalles Bibliográficos
Autores principales: Rossignol, Julien, Belaid, Zakia, Fouquet, Guillemette, Guillem, Flavia, Rignault, Rachel, Milpied, Pierre, Renand, Amédée, Coman, Tereza, D’Aveni, Maud, Dussiot, Michael, Colin, Elia, Levy, Jonathan, Carvalho, Caroline, Goudin, Nicolas, Cagnard, Nicolas, Côté, Francine, Babdor, Joel, Bhukhai, Kanit, Polivka, Laura, Bigorgne, Amélie E., Halse, Héloise, Marabelle, Aurélien, Mouraud, Séverine, Lepelletier, Yves, Maciel, Thiago T., Rubio, Marie-Thérèse, Heron, Delphine, Robert, Caroline, Girault, Isabelle, Lebeherec, Doris, Scoazec, Jean-Yves, Moura, Ivan, Condon, Louise, Weimershaus, Mirjana, Pages, Franck, Davoust, Jean, Gross, David, Hermine, Olivier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9301874/
https://www.ncbi.nlm.nih.gov/pubmed/35874918
http://dx.doi.org/10.1016/j.isci.2022.104353