Alcohol dependence and withdrawal increase sensitivity of central amygdalar GABAergic synapses to the glucocorticoid receptor antagonist mifepristone in male rats

Aberrant glucocorticoid signaling via glucocorticoid receptors (GR) plays a critical role in alcohol use disorder (AUD). Acute alcohol withdrawal and protracted abstinence in dependent rats are associated with increased GR signaling and changes in GR-mediated transcriptional activity in the rat cent...

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Detalles Bibliográficos
Autores principales: Khom, Sophia, Rodriguez, Larry, Gandhi, Pauravi, Kirson, Dean, Bajo, Michal, Oleata, Christopher S., Vendruscolo, Leandro F., Mason, Barbara J., Roberto, Marisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9301881/
https://www.ncbi.nlm.nih.gov/pubmed/34995754
http://dx.doi.org/10.1016/j.nbd.2022.105610

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9301881/
https://www.ncbi.nlm.nih.gov/pubmed/34995754
http://dx.doi.org/10.1016/j.nbd.2022.105610

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