Impact of Bioconjugation on Structure and Function of Antibodies for Use in Immunoassay by Hydrogen-Deuterium Exchange Mass Spectrometry

Monoclonal antibodies (mAbs) are widely used as analytical components in immunoassays to detect target molecules in applications such as clinical diagnostics, food analysis and drug discovery. Functional groups are often conjugated to lysine or cysteine residues to aid immobilization of mAbs or to e...

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Detalles Bibliográficos
Autores principales: Luckau, Luise, Groves, Kate, Blencowe, Chris, Scrimshaw, Sam, Dent, Alastair, Quaglia, Milena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9301968/
https://www.ncbi.nlm.nih.gov/pubmed/35874615
http://dx.doi.org/10.3389/fmolb.2022.866843

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9301968/
https://www.ncbi.nlm.nih.gov/pubmed/35874615
http://dx.doi.org/10.3389/fmolb.2022.866843

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