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High Expression of PARP1 in Tumor and Stroma Cells Predicts Different Prognosis and Platinum Resistance in Patients With Advanced Epithelial Ovarian Cancer

OBJECTIVE: This study aimed to explore the roles of PARP1 mRNA and protein expression in platinum resistance and prognosis of EOC patients, and reveal the different roles of PARP1 protein in epithelial tumor and stroma cells. METHODS: The PARP1 mRNA expression of the EOC tissues was examined by RT-q...

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Detalles Bibliográficos
Autores principales: Zuo, Wei-Wei, Zhao, Chun-Fang, Li, Yan, Sun, Hai-Yan, Ma, Guo-Ming, Liu, Yue-Ping, Kang, Shan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9301997/
https://www.ncbi.nlm.nih.gov/pubmed/35875162
http://dx.doi.org/10.3389/fonc.2022.931445